Количество страниц: 6 с.
Over the period from 2011 to 2016, an increase in proportion of multidrug-resistant cases among pulmonary tuberculosis patients with positive microscopy and/or culture (MTB+) has been observed in Ust-Aldansky district of the Sakha Republic (Yakutia). Proportion of multidrug-resistant (MDR) cases among newly identified patients increased by a factor of 1.2 (from 27.3% to 33.3%), but remained below the all-republic level (34.6%). It should be bared in mind, that in most (68.4%) patients with MDR, resistance is, as a rule, to 3-5 or more antitubercular agents. Effective outcomes in patients, who were started on chemotherapy regimen IV during the period from 2011 to 2014, were observed in 64%, while 4% had treatment failure. We observed high rates of treatment interruptions (12%), mortality from tuberculosis (12%), and proportions of cases transferred out to Directorate of Penitentiary Service (8%), which was attributed to the majority of patients with MDR belonging to socially marginalized population groups (65.8%) often associated with treatment non-compliance and defaulting from regular medical check-ups. Successful treatment outcome in patients with MDR largely depends on well-orchestrated work of all relevant agencies, and primarily, must be supported by heads of local administrations and active members of communities in each of the districts, ‘naslegs', or settlements. All these efforts should be aimed at making sure to hospitalize these categories of patients for motivated long-term treatment
Бурнашев, И. П.Характеристика и исходы лечения больных туберкулезом с множественной лекарственной устойчивостью в Усть-Алданском районе Якутии / И. П. Бурнашев, Л. П. Яковлева // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 18-22.
Количество страниц: 4 с.
Presented are trends over time (2012-2016) in key epidemiological indicators for tuberculosis in Megino-Kangalassky district of the Sakha Republic (Yakutia), a region with high risk of tuberculosis transmission. Negative trend to increase in multidrug-resistant tuberculosis has been observed. Nevertheless, by conducting a scope of multifaceted measures, we were able to meaningfully improve treatment effectiveness in new cases, and effectiveness of regular medical check-up of existing pool of tuberculosis patients
Борисова, Е. С. Эпидемиологическая ситуация по туберкулезу и показатели туберкулеза множественной лекарственной устойчивостью в Мегино-Кангаласском районе Якутии / Е. С. Борисова // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 12-14.
Количество страниц: 4 с.
Tuberculosis remains a social disease with a high prevalence over the world. The problem of tuberculosis is inseparable from the deterioration in population socio-economic standard of living. Tuberculosis infection reservoir is currently observed to grow, largely due to risk groups, and primarily, vulnerable, socially marginalized population groups. Socially vulnerable groups include homeless individuals, internal and external (near and far abroad), refugees from zones of ethnic or local military conflicts, unemployed, chronic alcohol and drug abusers, prisoners, and residents of shelters for disabled or elderly people. Social marginalization (so called de-adaptation) is the core underlying reason to why these patient groups have higher detection rates of extensive destructive tuberculosis with advanced stages or with primary drug resistance (including multidrug resistance), associated, as a result, with low success rates of multimodal treatment
Организация и проведение профилактического флюорографического обследования социально уязвимой группы населения г. Якутска / Е. Д. Апросимов, Л. П. Шепелева, А. М. Лукина и [другие] // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 10-12.
Количество страниц: 8 с.
Analysis of trends in statistics for smear-positive patients (MTB+) over the period from 2011 to 2016 showed that number of registered MTB+ patients with active pulmonary tuberculosis had decreased during the study period, both among all cases, and among new cases. Nonetheless, the size of infection reservoir defined as the number of MTB+ patients remains at high levels. We observed high rates of prevalence for drug-resistance, including multidrug resistance and extensive drug resistance (MDR and XDR). Prevalence rates of tuberculosis cases with MDR in Yakutia in the years 2013 to 2015 were higher than the same rates over Russian Federation by factors of 1.7-1.8-1.6, but showed a trend to decrease compared to the rates in the Far East Federal District. High proportion of newly identified patients with MDR among patients with drug-resistant tuberculosis (up to 68.5%) suggests the emergence of a totally new-made tuberculosis infection reservoir with resistance to first-line drugs. The policy pursued and supported in the Sakha Republic (Yakutia) is aimed at strengthening laboratory capabilities, adopting novel diagnostic technologies, improving epidemiologic surveillance, while supporting the currently running state programs against tuberculosis, and considering the currently observed decrease in tuberculosis incidence, this could lead to beneficial effect on existing and future burden of drug-resistant tuberculosis
Микробиологическая диагностика туберкулеза в Республике Саха (Якутия) / Г. И. Алексеева, М. В. Черных, Н. Г. Павлов [и другие] // Предупреждение распространения туберкулезной инфекции в циркумполярных регионах России. Актуальные проблемы сочетанных инфекций (ВИЧ/ТБ/гепатиты) — 2018. — С. 3-10.
Количество страниц: 4 с.
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Патология. Клиническая медицина > Фтизиатрия,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Патология. Клиническая медицина > Ревматология,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Патология. Клиническая медицина > Фтизиатрия,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Патология. Клиническая медицина > Ревматология.
Thoracic surgery specialty had been developed in Russia since the postwar years, but was officially established as a specialty in 1996. Absolute majority of thoracic surgical operations in the USSR were performed in anti-tuberculosis institutions. In Yakutia, thoracic surgery developed in three stages: start-up, assimilation of new techniques, development and introduction of in-house original methods of surgery
Кравченко, А. Ф. Влияние токоропластики на кардио-респираторную и иммунную системы больных туберкулезом / А. Ф. Кравченко // Якутский медицинский журнал. — 2013. — N 1 (41). — С. 73-76.
Количество страниц: 6 с.
Computed tomography (CT) was performed to examine 2429 children in order to increase the quality of early diagnosis of primary tuberculosis. Comparative analysis of CT referral diagnoses and CT opinions established that pathological changes in the lung and mediastenum were undetectable in more than half (57%) of the children referred for CT; the share of a local tuberculous process in the tuberculosis risk groups reduced from 52.8 to 11.2%; there was an increase in the share of nonspecific inflammatory changes and a decrease in the number of lung and mediastenial neoplasms after CT studies. The use of CT substantially expands the capacity of differential diagnosis of lung diseases and can considerably reduce the number of diagnostic errors. For optimization of radiotherapy for primary tuberculosis, CT is recommended for children of certain categories: long Mycobacterium tuberculosis-infected children with increasing tuberculin sensitivity in the early period of primary tuberculous infection with hyperergic reactions, children in contact with a tuberculosis patient, and those with unknown pathology of chest organs
Шепелева, Л. П. Доказательная диагностика первичного туберкулеза у детей / Л. П. Шепелева, А. Ф. Кравченко // Туберкулез и болезни легких. — 2010. — Т. 87, N 7. — С. 42-47.
Количество страниц: 6 с.
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Гигиена. Санитария,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Патология. Клиническая медицина > Фтизиатрия,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Гигиена. Санитария,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Патология. Клиническая медицина > Фтизиатрия.
A socially oriented procedure for regular medical check-up and organization of treatment in socially disadapted patients with pulmonary tuberculosis was developed, which was applied to 86 patients. A control group comprised 83 socially disadapted patients followed up by the conventional procedure for regular medical check-up and registration. A differential approach to organizing a regular medical check-up with a complex medical, social, and legal orientation allows a positive motivation for collaboration with medical staff and for treatment adherence to be formed in socially disadapted patients with pulmonary tuberculosis. In terms of cure rates, their treatment efficiency in first detected and one-year registered patients increased by 1.8 and 2.4 times, respectively
Лукина, А. М. Организация диспансерского наблюдения и лечения социально-дезадаптированных больных туберкулезом органов дыхания / А. М. Лукина // Туберкулез и болезни легких. — 2010. — Т. 87, N 7. — С. 29-34.
Количество страниц: 2 с.
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Патология. Клиническая медицина > Фтизиатрия,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Ортопедия. Хирургия. Офтальмология,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Патология. Клиническая медицина > Фтизиатрия,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Ортопедия. Хирургия. Офтальмология.
Винокуров, И. И. К вопросу о бактрионосительстве микобактерий туберкулеза / И. И. Винокуров, А. Ф. Кравченко, В. Е. Шамаев // Туберкулез и болезни легких. — 2011. — Т. 88, N 4. — С. 87.
Количество страниц: 2 с.
- Общественные науки. Образование > Право. Юридические науки > Государственное право. Конституционное право. Административное право,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Патология. Клиническая медицина > Фтизиатрия,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Патология. Клиническая медицина > Фтизиатрия,
- НАУКА ЯКУТИИ > ОБЩЕСТВЕННЫЕ НАУКИ > Право. Юридические науки.
Кравченко, А. Ф. Организационно-правовые проблемы предупреждения распространения туберкулеза в России / А. Ф. Кравченко // Туберкулез и болезни легких. — 2011. — Т. 88, N 4. — С. 216-217.
Количество страниц: 6 с.
- Математика. Естественные науки > Общая биология. Антропология. Вирусология. Микробиология,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Организация здравоохранения и общественное здоровье,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Патология. Клиническая медицина > Фтизиатрия,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Патология. Клиническая медицина > Фтизиатрия,
- НАУКА ЯКУТИИ > МАТЕМАТИКА. ЕСТЕСТВЕННЫЕ НАУКИ > Общая биология. Антропология. Вирусология. Микробиология,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Организация здравоохранения и общественное здоровье.
During the COVID-19 pandemic in the Russian Federation associated with restrictions and quarantine, in order to ensure the quality and availability of tuberculosis medical care to the population of the Republic of Sakha, it became necessary to improve and search for new organizational forms of out-patient care. The objective of the study: to analyze the use of new technologies in out-patient care for tuberculosis patients in the Republic of Sakha (Yakutia) during the COVID-19 pandemic. Result: Scientific Practical Phthisiology Center introduced the following information and digital technologies to ensure the availability and quality of medical services to the population of the republic during the COVID-19 pandemic: Cloud Polyclinic, Telemedical Consultations, Radiological Information System of APK ArchiMed , Video-Controlled Treatment at Home, and Hospital at Home. All technologies have demonstrated their efficacy for remote medical consultations and contacting patients online. Based on practical experience, these technologies provided the following: improvement of medical care provided to the population through consultations, maintaining good contact with the patient, monitoring patients' well-being, and drug in-take. They assured compliance with general federal and regional anti-epidemic recommendations to prevent the spread of the new coronavirus infection
Внедрение новых технологий по амбулаторно-поликлинической помощи больных туберкулезом в условиях пандемии covid-19 в Республике Саха (Якутия) / А. Ф. Кравченко, Е. С. Прокопьев, Л. П. Яковлева [и другие] // Туберкулез и болезни легких. — Т. 98, N 12. — 2020. — С. 20-24.
DOI: 10.21292/2075-1230-2020-98-12-20-24